PDF Fat Chance:A Story of Large Proportions!

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The liver processes triglycerides and controls their release. The triglycerides are combined with special proteins to form tiny spheres called lipoproteins which are sent into the bloodstream to circulate among the cells of your body. When the release or 'secretion' of lipoproteins from the liver is interrupted or the flow of triglycerides to the liver is increased, there will be a build-up of fat in your liver cells.

This condition is very rare and may lead rapidly to liver failure. Please see our Liver Health section for more information. Consuming too much alcohol can cause an accumulation of fat in the liver and can spur the liver to make triglycerides.

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If alcohol is the cause of fatty liver disease it is called Alcohol-related fatty liver disease see our 'Alcohol and liver disease' publication. It was not thought to progress to chronic long-term or serious liver disease.

For many people, a fatty liver can remain free of inflammation and they will experience few symptoms. In some people this can progress to a potentially life-threatening condition known as Cirrhosis. Today, NAFLD is recognised as one of the most common forms of liver disease worldwide and one that can progress to advanced liver damage. NAFLD is characterised by the build-up of excess fat in the liver of people who do not drink more than recommended guideline amounts of alcohol.

The first stage is fatty liver, or steatosis. This is where fat accumulates in the liver cells without any inflammation or scarring. NASH is a more significant condition, as it may cause scarring to the liver and can progress to cirrhosis. Non-alcohol related fatty liver or steatosis 2. Non-alcohol related steatohepatitis NASH 3. NASH with fibrosis 4.

Fat Chance: A Story of Large Proportions!

NAFLD can affect a wide range of people. In general, the more overweight you are, the more chance there is that you may have the condition. NAFLD is typically seen in people aged around 50 and more commonly in men than women. This may cause swelling of your liver and discomfort around it. If you place your right hand over the lower right side of your ribs, it will cover the area of your liver. Over a long period of time, ongoing inflammation leads to a build-up of scar tissue in your liver. This process is known as fibrosis and can lead to cirrhosis.

NASH is now considered to be one of the main causes of cirrhosis; many cases of cryptogenic of unknown origin cirrhosis are now being recognised as being caused by NASH. Cirrhosis is usually the result of long-term, continuous damage to the liver.


This is when irregular bumps, known as nodules, replace the smooth liver tissue and the liver becomes harder. Indian J Endocr Metab ; Figure 1: Venus de Milo Click here to view. Figure 2: The woman of Willendorf Click here to view. Davidson G. Disarmed: The story of the Venus de Milo. New York: Alfred A. Knopf; Haiken E.

Venus Envy: A history of cosmetic surgery. Johns Hopkins Press; Witcombe CL. The Venus of Willendorf. You are commenting using your Twitter account. You are commenting using your Facebook account.

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